There is a very common touchscreen bug with the Oneplus One that can only be partly/temporarily fixed by a reboot and shows in several ways:
- Touchscreen less responsive at all times
- Touches are often not recognized (apparently triggered by heat)
- Ghost touches (apparently triggered by heat)
Although this seems to be in some way related to the hardware (because I could easily reproduce it by making it warmer), a new touchscreen firmware was published recently in the CyanogenMod 12.1 repository that seems to work arround the problem somehow. I can attest that installing the new firmware fixed the problem on two Oneplus Ones that I tried it on. Battery life is noticably worse though, but this is said to be fixed with some changes that were committed to the CM12.1 repository on June 2.